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THE PROBLEM OF ALZHEIMER'S

HOW SCIENCE, CULTURE, AND POLITICS TURNED A RARE DISEASE INTO A CRISIS AND WHAT WE CAN DO ABOUT IT

An outstanding primer that readers should put into the hands of their doctors.

A professor of medicine at the University of Pennsylvania delivers a lucid, opinionated history of the science, politics, and care involved in the fight against this century’s most problematic disease.

The first symptom of Alzheimer’s is usually difficulty with memory, often recognized by a spouse, friend, or caregiver. Over years, memory deteriorates, and victims can no longer perform simple tasks such as paying bills or taking medicine. As the disease worsens, they become apathetic or delusional; lose the ability to dress, feed, and clean themselves; become bedridden and depressed; and often die from complications. Caring for an affected spouse or parent is a crushing experience, often bankrupting all but the wealthy because medical insurance and Medicare pay for medicine and doctor visits but not “custodial care,” which is estimated at as many as 170 hours per month. As Karlawish shows, Alzheimer’s usually causes more suffering for the caregiver than the patient. Until the 1970s, most doctors explained that this was “senility,” a consequence of aging beyond the scope of medical science. Eventually, researchers realized they were dealing with an epidemic of brain disease. At the same time, patient advocacy groups formed to lobby Congress, which was amenable to providing funding. Formerly, doctors diagnosed Alzheimer’s by examining the brain after death. Observing and testing living patients was a major advance. In 2012, the FDA approved an ingenious brain scan that illuminates the areas damaged by Alzheimer’s. Sadly, Medicare won’t pay for the $3,000 test, which doesn’t directly help patients because no good treatment exists (several drugs purport to slow its progress, but many experts believe they’re worthless). A medical expert with a page-turning style, Karlawish is mostly successful in conveying optimism. Hopeful drugs are in the research pipeline, but even better news is that physicians, institutions, and advocacy organizations are adopting more imaginative and humane programs to care for victims both before and after their disease becomes crippling.

An outstanding primer that readers should put into the hands of their doctors.

Pub Date: Feb. 23, 2021

ISBN: 978-1-250-21873-5

Page Count: 336

Publisher: St. Martin's

Review Posted Online: Nov. 4, 2020

Kirkus Reviews Issue: Dec. 1, 2020

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FOOTBALL

A smart, rewarding consideration of football’s popularity—and eventual downfall.

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A wide-ranging writer on his football fixation.

Is our biggest spectator sport “a practical means for understanding American life”? Klosterman thinks so, backing it up with funny, thought-provoking essays about TV coverage, ethical quandaries, and the rules themselves. Yet those who believe it’s a brutal relic of a less enlightened era need only wait, “because football is doomed.” Marshalling his customary blend of learned and low-culture references—Noam Chomsky, meet AC/DC—Klosterman offers an “expository obituary” of a game whose current “monocultural grip” will baffle future generations. He forecasts that economic and social forces—the NFL’s “cultivation of revenue,” changes in advertising, et al.—will end its cultural centrality. It’s hard to imagine a time when “football stops and no one cares,” but Klosterman cites an instructive precedent. Horse racing was broadly popular a century ago, when horses were more common in daily life. But that’s no longer true, and fandom has plummeted. With youth participation on a similar trajectory, Klosterman foresees a time when fewer people have a personal connection to football, rendering it a “niche” pursuit. Until then, the sport gives us much to consider, with Klosterman as our well-informed guide. Basketball is more “elegant,” but “football is the best television product ever,” its breaks between plays—“the intensity and the nothingness,” à la Sartre—provide thrills and space for reflection or conversation. For its part, the increasing “intellectual density” of the game, particularly for quarterbacks, mirrors a broader culture marked by an “ongoing escalation of corporate and technological control.” Klosterman also has compelling, counterintuitive takes on football gambling, GOAT debates, and how one major college football coach reminds him of “Laura Ingalls Wilder’s much‑loved Little House novels.” A beloved sport’s eventual death spiral has seldom been so entertaining.

A smart, rewarding consideration of football’s popularity—and eventual downfall.

Pub Date: Jan. 20, 2026

ISBN: 9780593490648

Page Count: 304

Publisher: Penguin Press

Review Posted Online: Oct. 24, 2025

Kirkus Reviews Issue: Dec. 1, 2025

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A PEOPLE'S HISTORY OF THE UNITED STATES

For Howard Zinn, long-time civil rights and anti-war activist, history and ideology have a lot in common. Since he thinks that everything is in someone's interest, the historian—Zinn posits—has to figure out whose interests he or she is defining/defending/reconstructing (hence one of his previous books, The Politics of History). Zinn has no doubts about where he stands in this "people's history": "it is a history disrespectful of governments and respectful of people's movements of resistance." So what we get here, instead of the usual survey of wars, presidents, and institutions, is a survey of the usual rebellions, strikes, and protest movements. Zinn starts out by depicting the arrival of Columbus in North America from the standpoint of the Indians (which amounts to their standpoint as constructed from the observations of the Europeans); and, after easily establishing the cultural disharmony that ensued, he goes on to the importation of slaves into the colonies. Add the laborers and indentured servants that followed, plus women and later immigrants, and you have Zinn's amorphous constituency. To hear Zinn tell it, all anyone did in America at any time was to oppress or be oppressed; and so he obscures as much as his hated mainstream historical foes do—only in Zinn's case there is that absurd presumption that virtually everything that came to pass was the work of ruling-class planning: this amounts to one great indictment for conspiracy. Despite surface similarities, this is not a social history, since we get no sense of the fabric of life. Instead of negating the one-sided histories he detests, Zinn has merely reversed the image; the distortion remains.

Pub Date: Jan. 1, 1979

ISBN: 0061965588

Page Count: 772

Publisher: Harper & Row

Review Posted Online: May 26, 2012

Kirkus Reviews Issue: Jan. 1, 1979

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