A Maryland surgeon’s experimental, potentially revolutionary treatment sparks unexpectedly violent results in this novel.

Dr. Paul Laden quickly notices something peculiar about the new hit-and-run victim in the emergency room. Though the patient is alive, his heartbeat and breathing are so faint they don’t register on the hospital’s machines. Amazingly, Laden also spots a wound seemingly healing itself. Keeping mum about what he’s witnessed, the doctor wheels John Doe to his research lab at the hospital. Once he declares John dead, he can experiment on his sedated patient as much as he pleases. Laden soon determines that John’s blood can kill viruses, and his internal organs may be capable of regeneration. Without divulging specifics, so that the fame and resultant wealth will be his alone, Laden offers to pay for organ transplants for three patients residing in various states. He chooses intellectually disabled Evelyn Stroman; Tyler Carson, who has Down syndrome; and Jason Scott, who suffers from Parkinson’s. Laden is certainly hopeful but can’t quite anticipate the changes that these patients ultimately experience. What happens to them leads to a startling level of violence both within and outside the patients’ lives. Jefferson’s horror story is harsh, frightening, and frequently graphic. While the book initially centers on Laden and his experiments, the latter half shifts to the transplant recipients, primarily Evelyn. The author’s prose throughout is crisp, unflinchingly detailing scenes of rape, mutilation, and spurting blood. The majority of the characters are unsympathetic, particularly Evelyn’s appalling, callous mother, Margaret. As such, some individuals subjected to brutality won’t earn much pity from readers. This nevertheless does not allay the novel’s disconcerting tone, which courses through the entirety of the narrative. Specifics on John and his perplexing condition don’t surface until the end, though much of the plot remains unresolved by the sequel-teasing denouement.

An edgy, terrifying, and shocking tale for hardcore horror fans.