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FROM ONE CELL

A JOURNEY INTO LIFE'S ORIGINS AND THE FUTURE OF MEDICINE

An authoritative account of a critical area of medical research and the promises it holds.

Cell research has the potential to unlock a new generation of treatments, according to a leader in the field.

Medical research is a series of small steps, each one building on the lessons learned before. This is the story that gastroenterologist Stanger, who combines cutting-edge research with clinical work, tells in this book. Embryos have long been recognized as the initial phase of life, but they raise the intriguing questions of how cells multiply, how they differentiate and coalesce to form organs, and how they eventually die. Through a series of biographical sketches, Stanger traces the gradual development of the knowledge base, including the unlocking of the connection between cells and genes. Ingenious experiments with frogs and flies provided an understanding of hereditary characteristics and mutations. Many of the breakthroughs came from strange places, such as studies of radiation poisoning, the structure of viruses, and the way that tumors grow. The discovery of DNA was a crucial step, and it paved the way for genetic engineering. Stanger has a particular interest in regenerative medicine, an emerging field that owes much to an understanding of embryo development. It uses cell-based procedures to repair damaged organs, potentially even spinal cords. There are also applications in the treatment of cancer and cognitive decline. The author also highlights important research into the development and transplantation of organs grown artificially. Stanger emphasizes that there is a long way to go, but the potential is huge. Due to the subject matter, parts of the book are complex and require a close reading, but there is a useful glossary of terms, and Stanger does his best to avoid jargon. Ultimately, the author delivers an informative package of how this field of medicine has developed and where it might be going.

An authoritative account of a critical area of medical research and the promises it holds.

Pub Date: Aug. 8, 2023

ISBN: 9781324005421

Page Count: 320

Publisher: Norton

Review Posted Online: May 23, 2023

Kirkus Reviews Issue: June 15, 2023

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I'M YOUR HUCKLEBERRY

A MEMOIR

An above-average celebrity memoir from an intriguing spirit.

The longtime Hollywood actor looks back.

“What does it mean to be a ham?” asks the author, rhetorically. “Was I a ham? I was naturally and inordinately theatrical. I liked to carry on. I liked attention. I liked extravagant speech. I liked to emote. I liked to talk.” All of these qualities are abundantly evident in Kilmer’s memoir, which is as much a spiritual journey as it is a chronicle of his life and career. The author recounts the depth of his Christian Science faith, his formative years in a family of privilege in Los Angeles, his teenage romance with fellow actor Mare Winningham (“my first real girlfriend”), his training and rebellion at Juilliard, and his decision to leave Broadway for Hollywood. There, he writes, “I was not yet a burgeoning talent but ‘Cher’s lover,’ ” when she was in her mid-30s and he in his early-20s. After scoring big with Tom Cruise in Top Gun, Kilmer turned down Blue Velvet and Dirty Dancing: “Neither part spoke to me.” He played Jim Morrison in Oliver Stone’s The Doors, which he considers “one of the proudest moments of my career.” Marlon Brando and Sam Shepard went from being idols that Kilmer worshipped to becoming friends. He was slated to star as Batman in three films but jumped ship after Batman Forever, which he considers “so bad, it’s almost good.” He married and divorced British actor Joanne Whalley and wooed Daryl Hannah (“kind of the female me, only better”), and he wrote and starred in a one-man show as Mark Twain. When he was hospitalized for surgery due to his throat cancer, he prayed, he read Twain and Christian Science’s Mary Baker Eddy, and he “didn’t wrestle with my angels. I sang and danced with them.” Kilmer was never a shrinking violet, and he still refuses to wilt.

An above-average celebrity memoir from an intriguing spirit. (photos)

Pub Date: April 21, 2020

ISBN: 978-1-9821-4489-0

Page Count: 320

Publisher: Simon & Schuster

Review Posted Online: March 11, 2020

Kirkus Reviews Issue: April 1, 2020

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F*CK IT, I'LL START TOMORROW

The lessons to draw are obvious: Smoke more dope, eat less meat. Like-minded readers will dig it.

The chef, rapper, and TV host serves up a blustery memoir with lashings of self-help.

“I’ve always had a sick confidence,” writes Bronson, ne Ariyan Arslani. The confidence, he adds, comes from numerous sources: being a New Yorker, and more specifically a New Yorker from Queens; being “short and fucking husky” and still game for a standoff on the basketball court; having strength, stamina, and seemingly no fear. All these things serve him well in the rough-and-tumble youth he describes, all stickball and steroids. Yet another confidence-builder: In the big city, you’ve got to sink or swim. “No one is just accepted—you have to fucking show that you’re able to roll,” he writes. In a narrative steeped in language that would make Lenny Bruce blush, Bronson recounts his sentimental education, schooled by immigrant Italian and Albanian family members and the mean streets, building habits good and bad. The virtue of those habits will depend on your take on modern mores. Bronson writes, for example, of “getting my dick pierced” down in the West Village, then grabbing a pizza and smoking weed. “I always smoke weed freely, always have and always will,” he writes. “I’ll just light a blunt anywhere.” Though he’s gone through the classic experiences of the latter-day stoner, flunking out and getting arrested numerous times, Bronson is a hard charger who’s not afraid to face nearly any challenge—especially, given his physique and genes, the necessity of losing weight: “If you’re husky, you’re always dieting in your mind,” he writes. Though vulgar and boastful, Bronson serves up a model that has plenty of good points, including his growing interest in nature, creativity, and the desire to “leave a legacy for everybody.”

The lessons to draw are obvious: Smoke more dope, eat less meat. Like-minded readers will dig it.

Pub Date: April 20, 2021

ISBN: 978-1-4197-4478-5

Page Count: 184

Publisher: Abrams

Review Posted Online: May 5, 2021

Kirkus Reviews Issue: June 1, 2021

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