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WHO WE ARE AND HOW WE GOT HERE

ANCIENT DNA AND THE NEW SCIENCE OF THE HUMAN PAST

Not an easy read, but an eye-opening account of significant scientific advances that throw a spectacular, often unexpected...

A surprising new description of how Homo sapiens originated in Africa and spread around the world.

In his first book, Reich (Genetics/Harvard Medical School) describes the revolution in his specialty, genomics, the branch of molecular biology that analyzes our genes, units of DNA that transmit hereditary information from parent to offspring. Since 2001, when scientists sequenced the human genome for the first time, technology has massively reduced the cost of the procedure. At the same time, researchers have become incredibly adept at extracting DNA from bones as old as 400,000 years. Readers who pay close attention will understand Reich’s explanation of what this reveals. As generations pass, strings of DNA in the genome split and recombine, and errors (mutations) appear in individual genes. Comparing one genome to another reveals the relationship between populations more accurately than comparing bones. Mutations appear at a regular rate, allowing researchers to measure time elapsed as evolution proceeds. “Since 2009,” writes the author, “…whole-genome data have begun to challenge long-held views in archaeology, history, anthropology, and even linguistics—and to resolve controversies in those fields. The ancient DNA revolution is rapidly disrupting our assumptions about the past.” Most agree that migrants from Turkey brought agriculture to Europe about 8,000 years ago. They once agreed that these migrants brought Indo-European languages spoken throughout most Western nations, but the studies in genomics reveal that the languages arrived with later migrants: a “ghost population” from the Russian steppes who also moved east and contributed genes to American Indians. Throughout the book, Reich includes numerous timelines, graphs, maps, and diagrams to assist readers in visualizing his material, but those who are not scientifically inclined may find the narrative difficult to follow—though ultimately rewarding.

Not an easy read, but an eye-opening account of significant scientific advances that throw a spectacular, often unexpected light on human prehistory.

Pub Date: March 27, 2018

ISBN: 978-1-101-87032-7

Page Count: 368

Publisher: Pantheon

Review Posted Online: Feb. 14, 2018

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A PEOPLE'S HISTORY OF THE UNITED STATES

For Howard Zinn, long-time civil rights and anti-war activist, history and ideology have a lot in common. Since he thinks that everything is in someone's interest, the historian—Zinn posits—has to figure out whose interests he or she is defining/defending/reconstructing (hence one of his previous books, The Politics of History). Zinn has no doubts about where he stands in this "people's history": "it is a history disrespectful of governments and respectful of people's movements of resistance." So what we get here, instead of the usual survey of wars, presidents, and institutions, is a survey of the usual rebellions, strikes, and protest movements. Zinn starts out by depicting the arrival of Columbus in North America from the standpoint of the Indians (which amounts to their standpoint as constructed from the observations of the Europeans); and, after easily establishing the cultural disharmony that ensued, he goes on to the importation of slaves into the colonies. Add the laborers and indentured servants that followed, plus women and later immigrants, and you have Zinn's amorphous constituency. To hear Zinn tell it, all anyone did in America at any time was to oppress or be oppressed; and so he obscures as much as his hated mainstream historical foes do—only in Zinn's case there is that absurd presumption that virtually everything that came to pass was the work of ruling-class planning: this amounts to one great indictment for conspiracy. Despite surface similarities, this is not a social history, since we get no sense of the fabric of life. Instead of negating the one-sided histories he detests, Zinn has merely reversed the image; the distortion remains.

Pub Date: Jan. 1, 1979

ISBN: 0061965588

Page Count: 772

Publisher: Harper & Row

Review Posted Online: May 26, 2012

Kirkus Reviews Issue: Jan. 1, 1979

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WHEN BREATH BECOMES AIR

A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular...

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A neurosurgeon with a passion for literature tragically finds his perfect subject after his diagnosis of terminal lung cancer.

Writing isn’t brain surgery, but it’s rare when someone adept at the latter is also so accomplished at the former. Searching for meaning and purpose in his life, Kalanithi pursued a doctorate in literature and had felt certain that he wouldn’t enter the field of medicine, in which his father and other members of his family excelled. “But I couldn’t let go of the question,” he writes, after realizing that his goals “didn’t quite fit in an English department.” “Where did biology, morality, literature and philosophy intersect?” So he decided to set aside his doctoral dissertation and belatedly prepare for medical school, which “would allow me a chance to find answers that are not in books, to find a different sort of sublime, to forge relationships with the suffering, and to keep following the question of what makes human life meaningful, even in the face of death and decay.” The author’s empathy undoubtedly made him an exceptional doctor, and the precision of his prose—as well as the moral purpose underscoring it—suggests that he could have written a good book on any subject he chose. Part of what makes this book so essential is the fact that it was written under a death sentence following the diagnosis that upended his life, just as he was preparing to end his residency and attract offers at the top of his profession. Kalanithi learned he might have 10 years to live or perhaps five. Should he return to neurosurgery (he could and did), or should he write (he also did)? Should he and his wife have a baby? They did, eight months before he died, which was less than two years after the original diagnosis. “The fact of death is unsettling,” he understates. “Yet there is no other way to live.”

A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular clarity.

Pub Date: Jan. 19, 2016

ISBN: 978-0-8129-8840-6

Page Count: 248

Publisher: Random House

Review Posted Online: Sept. 29, 2015

Kirkus Reviews Issue: Oct. 15, 2015

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