GENOMICS

A geneticist and an author for young people provide a genome primer for teens.

In efficient, readable prose, this book walks readers through the history of humanity’s understanding and application of genetics to modern medicine. After contextualizing by using genomics to identify undiagnosed diseases, a foundational history lesson shows how genetic inheritance was theorized, described, and discovered (a process that started in 530 B.C.E.) and provides rundowns of basic genetic laws (with Punnett squares demonstrating dominant and recessive traits). A chapter on PKU (a disease that’s manageable through a special diet but causes lifelong intellectual disabilities if not caught early) walks readers through the early development of newborn screening, which grounds discussions of the nitty-gritty of DNA. Through sidebars and various perspectives, the authors’ multiple explanations and diagrams help to distill complicated information into easy-to-work-with concepts. Other chapters cover the development of medical DNA tests and commercial genetic testing (along with its limitations) before finally looking to the future potential of personalized genetic medicine. Every step of the way, ethical implications are tackled head-on—respect for members of the disability community is prioritized, eugenics is debunked and its application rightfully vilified, and discrimination on racial and transgender lines is confronted. This accessible introduction demystifies the complicated science. The authors strategically use scientific language and terminology paired with plainspoken explanations, and the colorful, varied physical layout enhances the reading experience.

High-quality, curiosity-sparking brain fuel.