A sober exploration of weight-loss pills that actually work.
A current overview of the drugs available for weight loss.
Journalist Hari, author of Chasing the Scream and Lost Connections, begins with a vivid description of his fascination with junk food, along with the oft-told story of the food industry’s post–World War II breakthrough in manufacturing calorie-dense, fatty, salty, chemically enhanced edible products, many not found in nature but irresistible to consumers. “The average American adult weighs twenty-three pounds more than in 1960,” writes the author, “and more than 70 percent of all Americans are either overweight or obese.” Unfortunately, diets rarely work. Weight-loss drugs, touted for decades, were mostly worthless; the few that worked turned out to be toxic. Following the history lesson, Hari reveals that the wildly popular drugs—Ozempic, Mounjaro, Wegovy—are effective. Six months after starting Ozempic, the author was thinner, fitter, and more confident, but also uneasy. He felt full soon after beginning a meal, food lacked its usual appeal, and he felt nauseous more than before. As he relates, 5% to 10% of users stop because the side effects aren’t worth it. However, the drugs have been treating diabetes for 18 years, so the odds of a patient developing a serious side effect seem small. In addition to his personal story, Hari chronicles his travels around the world interviewing users, researchers, physicians, and the drug’s developers, pausing for thoughtful essays on why we eat and overeat, why dieting almost never works, and how the world may change when these drugs become affordable after the patent expires in 2032. In a mildly optimistic conclusion, Hari argues that our first priority should be to eliminate the superprocessed quasi-foods that we can’t resist—unlikely, of course, so the author offers a digestible survey of the possibilities of pharmaceuticals.
A sober exploration of weight-loss pills that actually work.Pub Date: May 7, 2024
ISBN: 9780593728635
Page Count: 320
Publisher: Crown
Review Posted Online: May 10, 2024
Kirkus Reviews Issue: June 15, 2024
Maher calls out idiocy wherever he sees it, with a comedic delivery that veers between a stiletto and a sledgehammer.
The comedian argues that the arts of moderation and common sense must be reinvigorated.
Some people are born snarky, some become snarky, and some have snarkiness thrust upon them. Judging from this book, Maher—host of HBO’s Real Time program and author of The New New Rules and When You Ride Alone, You Ride With bin Laden—is all three. As a comedian, he has a great deal of leeway to make fun of people in politics, and he often delivers hilarious swipes with a deadpan face. The author describes himself as a traditional liberal, with a disdain for Republicans (especially the MAGA variety) and a belief in free speech and personal freedom. He claims that he has stayed much the same for more than 20 years, while the left, he argues, has marched toward intolerance. He sees an addiction to extremism on both sides of the aisle, which fosters the belief that anyone who disagrees with you must be an enemy to be destroyed. However, Maher has always displayed his own streaks of extremism, and his scorched-earth takedowns eventually become problematic. The author has something nasty to say about everyone, it seems, and the sarcastic tone starts after more than 300 pages. As has been the case throughout his career, Maher is best taken in small doses. The book is worth reading for the author’s often spot-on skewering of inept politicians and celebrities, but it might be advisable to occasionally dip into it rather than read the whole thing in one sitting. Some parts of the text are hilarious, but others are merely insulting. Maher is undeniably talented, but some restraint would have produced a better book.
Maher calls out idiocy wherever he sees it, with a comedic delivery that veers between a stiletto and a sledgehammer.Pub Date: May 21, 2024
ISBN: 9781668051351
Page Count: 384
Publisher: Simon & Schuster
Review Posted Online: March 5, 2024
Kirkus Reviews Issue: April 1, 2024
BOOK REVIEW
BOOK REVIEW
Skloot's meticulous, riveting account strikes a humanistic balance between sociological history, venerable portraiture and...
A dense, absorbing investigation into the medical community's exploitation of a dying woman and her family's struggle to salvage truth and dignity decades later.
In a well-paced, vibrant narrative, Popular Science contributor and Culture Dish blogger Skloot (Creative Writing/Univ. of Memphis) demonstrates that for every human cell put under a microscope, a complex life story is inexorably attached, to which doctors, researchers and laboratories have often been woefully insensitive and unaccountable. In 1951, Henrietta Lacks, an African-American mother of five, was diagnosed with what proved to be a fatal form of cervical cancer. At Johns Hopkins, the doctors harvested cells from her cervix without her permission and distributed them to labs around the globe, where they were multiplied and used for a diverse array of treatments. Known as HeLa cells, they became one of the world's most ubiquitous sources for medical research of everything from hormones, steroids and vitamins to gene mapping, in vitro fertilization, even the polio vaccine—all without the knowledge, must less consent, of the Lacks family. Skloot spent a decade interviewing every relative of Lacks she could find, excavating difficult memories and long-simmering outrage that had lay dormant since their loved one's sorrowful demise. Equal parts intimate biography and brutal clinical reportage, Skloot's graceful narrative adeptly navigates the wrenching Lack family recollections and the sobering, overarching realities of poverty and pre–civil-rights racism. The author's style is matched by a methodical scientific rigor and manifest expertise in the field.
Skloot's meticulous, riveting account strikes a humanistic balance between sociological history, venerable portraiture and Petri dish politics.Pub Date: Feb. 9, 2010
ISBN: 978-1-4000-5217-2
Page Count: 320
Publisher: Crown
Review Posted Online: Dec. 22, 2010
Kirkus Reviews Issue: Jan. 1, 2010
BOOK REVIEW
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