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BOTTLE OF LIES

THE INSIDE STORY OF THE GENERIC DRUG BOOM

An urgent, alarming work of health reporting that will make you question every drug in your medicine cabinet.

An eye-opening exposé on generic drugs.

Given the greed of pharmaceutical companies, writes investigative journalist Eban (Dangerous Doses: How Counterfeiters Are Contaminating America's Drug Supply, 2005), cheap generics are essential to money-strapped consumers—and that just may be a death sentence. There are many players and levels in this excellent book, a solid mix of the history of generic drugs, whistleblower tale, and pharmaceutical detective story. The whistleblower in question is a young executive and systems engineer from India, lured home after being educated in the United States to work for a huge pharmacological concern that specializes in making generic drugs. There’s a fortune to be made there, Eban writes, especially for the first to market, who can enjoy a brief monopoly. The margins are further improved by eliminating key steps in the quality-control process—and then cooking the books when investigators from the Food and Drug Administration come to inspect. The executive in question sounded the alarm, his charge backed by on-the-ground evidence from an FDA investigator. However, he faced prosecution, not least on the part of the FDA and U.S. attorney Rod Rosenstein. “My reporting,” writes Eban early on, “led me into a web of global deception”—and, she makes clear throughout this long but tightly narrated book, that deception may well prove fatal to medical consumers. This is especially true in the developing world, she writes, for if substandard drugs are regularly shipped from plants in India, China, and elsewhere to the U.S. and Europe, the really ineffective, dangerous stuff is headed for markets in Africa, South America, and Asia: EpiPens, AIDS cocktails, cures that may turn out to be poisons. For all the efforts of that FDA inspector, writes the author, the new antiregulatory FDA now gives foreign companies advance warning of inspections, allowing the deception to grow and flourish as suspect drugs continue to roll in, "including a crucial chemotherapy drug for treating leukemia and breast and ovarian cancers.”

An urgent, alarming work of health reporting that will make you question every drug in your medicine cabinet.

Pub Date: May 14, 2019

ISBN: 978-0-06-233878-5

Page Count: 512

Publisher: Ecco/HarperCollins

Review Posted Online: May 16, 2019

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GOOD ECONOMICS FOR HARD TIMES

Occasionally wonky but overall a good case for how the dismal science can make the world less—well, dismal.

“Quality of life means more than just consumption”: Two MIT economists urge that a smarter, more politically aware economics be brought to bear on social issues.

It’s no secret, write Banerjee and Duflo (co-authors: Poor Economics: A Radical Rethinking of the Way To Fight Global Poverty, 2011), that “we seem to have fallen on hard times.” Immigration, trade, inequality, and taxation problems present themselves daily, and they seem to be intractable. Economics can be put to use in figuring out these big-issue questions. Data can be adduced, for example, to answer the question of whether immigration tends to suppress wages. The answer: “There is no evidence low-skilled migration to rich countries drives wage and employment down for the natives.” In fact, it opens up opportunities for those natives by freeing them to look for better work. The problem becomes thornier when it comes to the matter of free trade; as the authors observe, “left-behind people live in left-behind places,” which explains why regional poverty descended on Appalachia when so many manufacturing jobs left for China in the age of globalism, leaving behind not just left-behind people but also people ripe for exploitation by nationalist politicians. The authors add, interestingly, that the same thing occurred in parts of Germany, Spain, and Norway that fell victim to the “China shock.” In what they call a “slightly technical aside,” they build a case for addressing trade issues not with trade wars but with consumption taxes: “It makes no sense to ask agricultural workers to lose their jobs just so steelworkers can keep theirs, which is what tariffs accomplish.” Policymakers might want to consider such counsel, especially when it is coupled with the observation that free trade benefits workers in poor countries but punishes workers in rich ones.

Occasionally wonky but overall a good case for how the dismal science can make the world less—well, dismal.

Pub Date: Nov. 12, 2019

ISBN: 978-1-61039-950-0

Page Count: 432

Publisher: PublicAffairs

Review Posted Online: Aug. 28, 2019

Kirkus Reviews Issue: Sept. 15, 2019

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#GIRLBOSS

Career and business advice for the hashtag generation. For all its self-absorption, this book doesn’t offer much reflection...

A Dumpster diver–turned-CEO details her rise to success and her business philosophy.

In this memoir/business book, Amoruso, CEO of the Internet clothing store Nasty Gal, offers advice to young women entrepreneurs who seek an alternative path to fame and fortune. Beginning with a lengthy discussion of her suburban childhood and rebellious teen years, the author describes her experiences living hand to mouth, hitchhiking, shoplifting and dropping out of school. Her life turned around when, bored at work one night, she decided to sell a few pieces of vintage clothing on eBay. Fast-forward seven years, and Amoruso was running a $100 million company with 350 employees. While her success is admirable, most of her advice is based on her own limited experiences and includes such hackneyed lines as, “When you accept yourself, it’s surprising how much other people will accept you, too.” At more than 200 pages, the book is overlong, and much of what the author discusses could be summarized in a few tweets. In fact, much of it probably has been: One of the most interesting sections in the book is her description of how she uses social media. Amoruso has a spiritual side, as well, and she describes her belief in “chaos magic” and “sigils,” a kind of wishful-thinking exercise involving abstract words. The book also includes sidebars featuring guest “girlbosses” (bloggers, Internet entrepreneurs) who share equally clichéd suggestions for business success. Some of the guidance Amoruso offers for interviews (don’t dress like you’re going to a nightclub), getting fired (don’t call anyone names) and finding your fashion style (be careful which trends you follow) will be helpful to her readers, including the sage advice, “You’re not special.”

Career and business advice for the hashtag generation. For all its self-absorption, this book doesn’t offer much reflection or insight.

Pub Date: May 6, 2014

ISBN: 978-0-399-16927-4

Page Count: 256

Publisher: Portfolio

Review Posted Online: June 22, 2014

Kirkus Reviews Issue: July 15, 2014

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