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SAVED BY SCIENCE

THE HOPE AND PROMISE OF SYNTHETIC BIOLOGY

Encouraging advances in biology delineated through accessible, inviting writing.

A survey of the new field of synthetic biology, “the science of building simple organisms or ‘biological apps’ to make manufacturing greener, energy production more sustainable, agriculture more robust and medicine more powerful and precise.”

In this energetic and optimistic book, Poznansky, former CEO of the Ontario Genomics Institute, shows how synthetic biology can be used to contend with major issues involving health, food, and the environment. This combination of engineering and molecular biology serves to design and build synthetic gene circuits and biomolecular components to reprogram organisms. The products are new life-forms, whether completely novel or partly modified. Examples include viruses that target specific diseased cells, genetically modified cells that remove heavy metals from lakes and rivers, and bacterium that take carbon out of the atmosphere. In layman’s terms, Poznansky explains this new world of unnatural selection and nonrandom mutation, evolution by human design. Although he is profoundly enthusiastic about the prospects of genomics technologies and engineering, he recognizes that we are at the beginning of a process that requires the safest and most appropriate approaches: genetic manipulation incorporating safety switches to ensure containment, further understanding of gene editing, insertion, and expression, and the avoidance of the new gene being identified as a foreign substance. With sensible language and peer-reviewed research, the author explores the present and coming needs regarding global health care, food security, and pollution and examines the history of genetically modified organisms. Of special concern are the roles of ethics and regulation regarding safety, public interest, risk vs. reward, and the potential detrimental interference of political skulduggery, special-interest groups, and large corporations. Poznansky also takes to task anti-vaxxers and those that doubt the severity of climate change, while lauding the grassroots efforts—“the democratization of science”—that have already shown some promising results.

Encouraging advances in biology delineated through accessible, inviting writing.

Pub Date: Sept. 22, 2020

ISBN: 978-1-77041-535-5

Page Count: 300

Publisher: ECW Press

Review Posted Online: June 11, 2020

Kirkus Reviews Issue: July 1, 2020

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ELON MUSK

Alternately admiring and critical, unvarnished, and a closely detailed account of a troubled innovator.

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A warts-and-all portrait of the famed techno-entrepreneur—and the warts are nearly beyond counting.

To call Elon Musk (b. 1971) “mercurial” is to undervalue the term; to call him a genius is incorrect. Instead, Musk has a gift for leveraging the genius of others in order to make things work. When they don’t, writes eminent biographer Isaacson, it’s because the notoriously headstrong Musk is so sure of himself that he charges ahead against the advice of others: “He does not like to share power.” In this sharp-edged biography, the author likens Musk to an earlier biographical subject, Steve Jobs. Given Musk’s recent political turn, born of the me-first libertarianism of the very rich, however, Henry Ford also comes to mind. What emerges clearly is that Musk, who may or may not have Asperger’s syndrome (“Empathy did not come naturally”), has nurtured several obsessions for years, apart from a passion for the letter X as both a brand and personal name. He firmly believes that “all requirements should be treated as recommendations”; that it is his destiny to make humankind a multi-planetary civilization through innovations in space travel; that government is generally an impediment and that “the thought police are gaining power”; and that “a maniacal sense of urgency” should guide his businesses. That need for speed has led to undeniable successes in beating schedules and competitors, but it has also wrought disaster: One of the most telling anecdotes in the book concerns Musk’s “demon mode” order to relocate thousands of Twitter servers from Sacramento to Portland at breakneck speed, which trashed big parts of the system for months. To judge by Isaacson’s account, that may have been by design, for Musk’s idea of creative destruction seems to mean mostly chaos.

Alternately admiring and critical, unvarnished, and a closely detailed account of a troubled innovator.

Pub Date: Sept. 12, 2023

ISBN: 9781982181284

Page Count: 688

Publisher: Simon & Schuster

Review Posted Online: Sept. 12, 2023

Kirkus Reviews Issue: Oct. 15, 2023

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F*CK IT, I'LL START TOMORROW

The lessons to draw are obvious: Smoke more dope, eat less meat. Like-minded readers will dig it.

The chef, rapper, and TV host serves up a blustery memoir with lashings of self-help.

“I’ve always had a sick confidence,” writes Bronson, ne Ariyan Arslani. The confidence, he adds, comes from numerous sources: being a New Yorker, and more specifically a New Yorker from Queens; being “short and fucking husky” and still game for a standoff on the basketball court; having strength, stamina, and seemingly no fear. All these things serve him well in the rough-and-tumble youth he describes, all stickball and steroids. Yet another confidence-builder: In the big city, you’ve got to sink or swim. “No one is just accepted—you have to fucking show that you’re able to roll,” he writes. In a narrative steeped in language that would make Lenny Bruce blush, Bronson recounts his sentimental education, schooled by immigrant Italian and Albanian family members and the mean streets, building habits good and bad. The virtue of those habits will depend on your take on modern mores. Bronson writes, for example, of “getting my dick pierced” down in the West Village, then grabbing a pizza and smoking weed. “I always smoke weed freely, always have and always will,” he writes. “I’ll just light a blunt anywhere.” Though he’s gone through the classic experiences of the latter-day stoner, flunking out and getting arrested numerous times, Bronson is a hard charger who’s not afraid to face nearly any challenge—especially, given his physique and genes, the necessity of losing weight: “If you’re husky, you’re always dieting in your mind,” he writes. Though vulgar and boastful, Bronson serves up a model that has plenty of good points, including his growing interest in nature, creativity, and the desire to “leave a legacy for everybody.”

The lessons to draw are obvious: Smoke more dope, eat less meat. Like-minded readers will dig it.

Pub Date: April 20, 2021

ISBN: 978-1-4197-4478-5

Page Count: 184

Publisher: Abrams

Review Posted Online: May 5, 2021

Kirkus Reviews Issue: June 1, 2021

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