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FOREIGN BODIES

PANDEMICS, VACCINES, AND THE HEALTH OF NATIONS

A vivid account of the horror of epidemics and the breakthroughs that can bring them under control.

A history of the contest between contagion and medical research.

Schama, a professor of history and art history at Columbia, has won numerous awards for his many books and TV documentaries. At first glance, a book dealing with diseases would not seem to be a good match for the author, but his methods work well with the subject. Schama focuses on the 18th and 19th centuries, chronicling the smallpox outbreak in London, the cholera epidemic in Paris, and the bubonic plague that swept through India. Smallpox killed tens of thousands, and there seemed to be no answer to it. Eventually, however, it was discovered that deliberately infecting people with a diluted dose could give them immunity against the virus. This seemed counterintuitive, and the medical establishment was solidly opposed to it (a recurring theme of the book). Nonetheless, the concept gradually took hold and became a founding principle of immunology. Cholera, being bacterial in nature, required a different approach, and Schama examines the various theories put forward on the way to the solutions of better sanitation and water filtration. Bubonic plague had been around for centuries, but its reemergence in the late 19th century caught researchers by surprise. Schama notes that a key figure in fighting it in India was the “saintly scientist” Waldemar Haffkine, a gifted microbiologist who developed many of the testing protocols that would eventually underpin the field. He was also instrumental in organizing a large-scale vaccination effort, saving an untold number of lives. This is a broad canvas, but Schama, a diligent and experienced historian, keeps the narrative on track, and he has a good eye for illustrative anecdotes. It adds up to a strong story that, in the shadow of the Covid-19 pandemic, speaks to us all.

A vivid account of the horror of epidemics and the breakthroughs that can bring them under control.

Pub Date: Sept. 19, 2023

ISBN: 9781328974839

Page Count: 480

Publisher: Ecco/HarperCollins

Review Posted Online: May 31, 2023

Kirkus Reviews Issue: July 1, 2023

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ELON MUSK

Alternately admiring and critical, unvarnished, and a closely detailed account of a troubled innovator.

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A warts-and-all portrait of the famed techno-entrepreneur—and the warts are nearly beyond counting.

To call Elon Musk (b. 1971) “mercurial” is to undervalue the term; to call him a genius is incorrect. Instead, Musk has a gift for leveraging the genius of others in order to make things work. When they don’t, writes eminent biographer Isaacson, it’s because the notoriously headstrong Musk is so sure of himself that he charges ahead against the advice of others: “He does not like to share power.” In this sharp-edged biography, the author likens Musk to an earlier biographical subject, Steve Jobs. Given Musk’s recent political turn, born of the me-first libertarianism of the very rich, however, Henry Ford also comes to mind. What emerges clearly is that Musk, who may or may not have Asperger’s syndrome (“Empathy did not come naturally”), has nurtured several obsessions for years, apart from a passion for the letter X as both a brand and personal name. He firmly believes that “all requirements should be treated as recommendations”; that it is his destiny to make humankind a multi-planetary civilization through innovations in space travel; that government is generally an impediment and that “the thought police are gaining power”; and that “a maniacal sense of urgency” should guide his businesses. That need for speed has led to undeniable successes in beating schedules and competitors, but it has also wrought disaster: One of the most telling anecdotes in the book concerns Musk’s “demon mode” order to relocate thousands of Twitter servers from Sacramento to Portland at breakneck speed, which trashed big parts of the system for months. To judge by Isaacson’s account, that may have been by design, for Musk’s idea of creative destruction seems to mean mostly chaos.

Alternately admiring and critical, unvarnished, and a closely detailed account of a troubled innovator.

Pub Date: Sept. 12, 2023

ISBN: 9781982181284

Page Count: 688

Publisher: Simon & Schuster

Review Posted Online: Sept. 12, 2023

Kirkus Reviews Issue: Oct. 15, 2023

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THE IMMORTAL LIFE OF HENRIETTA LACKS

Skloot's meticulous, riveting account strikes a humanistic balance between sociological history, venerable portraiture and...

A dense, absorbing investigation into the medical community's exploitation of a dying woman and her family's struggle to salvage truth and dignity decades later.

In a well-paced, vibrant narrative, Popular Science contributor and Culture Dish blogger Skloot (Creative Writing/Univ. of Memphis) demonstrates that for every human cell put under a microscope, a complex life story is inexorably attached, to which doctors, researchers and laboratories have often been woefully insensitive and unaccountable. In 1951, Henrietta Lacks, an African-American mother of five, was diagnosed with what proved to be a fatal form of cervical cancer. At Johns Hopkins, the doctors harvested cells from her cervix without her permission and distributed them to labs around the globe, where they were multiplied and used for a diverse array of treatments. Known as HeLa cells, they became one of the world's most ubiquitous sources for medical research of everything from hormones, steroids and vitamins to gene mapping, in vitro fertilization, even the polio vaccine—all without the knowledge, must less consent, of the Lacks family. Skloot spent a decade interviewing every relative of Lacks she could find, excavating difficult memories and long-simmering outrage that had lay dormant since their loved one's sorrowful demise. Equal parts intimate biography and brutal clinical reportage, Skloot's graceful narrative adeptly navigates the wrenching Lack family recollections and the sobering, overarching realities of poverty and pre–civil-rights racism. The author's style is matched by a methodical scientific rigor and manifest expertise in the field.

Skloot's meticulous, riveting account strikes a humanistic balance between sociological history, venerable portraiture and Petri dish politics.

Pub Date: Feb. 9, 2010

ISBN: 978-1-4000-5217-2

Page Count: 320

Publisher: Crown

Review Posted Online: Dec. 22, 2010

Kirkus Reviews Issue: Jan. 1, 2010

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