John Green will tackle tuberculosis in a new nonfiction book for young readers.

Crash Course Books, a new imprint of Penguin Young Readers, will publish Green’s Everything Is Tuberculosis: The History and Persistence of Our Deadliest Infection, next year. The press describes the book as “a deeply human story illuminating the fight against the world’s deadliest disease.”

Green is best known for his phenomenally popular young adult novels, including Looking for Alaska and The Fault in Our Stars, and for the Vlogbrothers YouTube channel that he created with his brother, fellow author Hank Green.

His new book, Penguin says, was inspired by Henry, a young tuberculosis patient whom he met in Sierra Leone. “In Everything Is Tuberculosis, John tells Henry’s story, woven through with the scientific and social histories of how tuberculosis has shaped our world and how our choices will shape the future of tuberculosis,” the publisher says.

In a YouTube video announcement of the book, Green said that “Everything Is Tuberculosis is a science story about how we came to understand TB as an infectious disease, and eventually developed a cure for it, but it’s also a human story about why we’ve done such a terrible job of distributing that cure to the people who need it most. And especially it’s the story of one boy trying to survive drug-resistant tuberculosis.”

Everything Is Tuberculosis is scheduled for publication on March 18, 2025.

Michael Schaub is a contributing writer.